When Tony opens a mysterious letter thinking it's for him, a small puff of white powder comes out and releases a possible deadly virus. Soon Kate and Tony are isolated in a bio-hazard isolation room for precaution. McGee and Gibbs work to discover who sent the envelope and how to cure their friends before it's too late for them.
Sean Murray
as Timothy McGee
Wilmer Valderrama
as Nick Torres
Katrina Law
as Jessica Knight
Brian Dietzen
as Jimmy Palmer
Rocky Carroll
as Leon Vance
Diona Reasonover
as Kasie Hines
Gary Cole
as Alden Parker
Brian Dietzen
as Jimmy Palmer
Olivia Burnette
as Sarah Lowell
Tamara Taylor
as Cassie Yates
Mariette Hartley
as Hanna Lowell
Steven Eckholdt
as Brad Pitt
Rizwan Manji
as Dr. Pandy
Emily Wilson
as Young Hanna Lowell (uncredited)
Donald P. Bellisario
as Doctor at Bethesda (uncredited)