- David Letterman (Self - Host)
- Paul Shaffer (Self -Musical Director)
- Alan Kalter (Self - Announcer (voice))
Late Show with David Letterman — S13E51
Episode: George Clooney, Ashlee Simpson
Air Date: 2005-11-21
Overview
Dave shocks the audience with the news that Oprah Winfrey will be a guest on the show a week from Thursday; Biff undergoes Lasek eye surgery; George Clooney promotes "Syriana."