- Hugh Laurie (Gregory House)
- Robert Sean Leonard (James Wilson)
- Omar Epps (Eric Foreman)
- Jesse Spencer (Robert Chase)
- Odette Annable (Jessica Adams)
- Peter Jacobson (Chris Taub)
- Lo Mutuc (Chi Park)
Episode: After Hours
Air Date: 2011-05-16
Runtime: 44 min
When House discovers that the experimental drug he's been using causes fatal tumors, he decides to attempt to excise them himself. However, he can't complete the surgery and ends up needing Cuddy's help. Meanwhile, Thirteen's friend from prison (Amy Landecker), a relapsed drug user, arrives at her apartment needing medical care after being stabbed. With her friend unwilling to go to the hospital, Thirteen enlists Chase's assistance when the friend loses sensation and movement in her arm. Also, Taub receives some unexpected news that could change his life.