Grey's Anatomy — Season 21, Episode 1

• 
  Ellen Pompeo
  as Meredith Grey
• 
  Chandra Wilson
  as Miranda Bailey
• 
  James Pickens Jr.
  as Richard Webber
• 
  Caterina Scorsone
  as Amelia Shepherd
• 
  Camilla Luddington
  as Jo Wilson
• 
  Kevin McKidd
  as Owen Hunt
• 
  Kim Raver
  as Teddy Altman
• 
  Jason George
  as Ben Warren
• 
  Chris Carmack
  as Atticus Lincoln
• 
  Anthony Hill
  as Winston Ndugu
• 
  Adelaide Kane
  as Jules Millin
• 
  Alexis Floyd
  as Simone Griffith
• 
  Niko Terho
  as Lucas Adams
• 
  Harry Shum Jr.
  as Benson 'Blue' Kwan
• 
  Trevor Jackson
  as Wes Bryant

• 
  Jesse Williams
  as Jackson Avery
• 
  Jake Borelli
  as Levi Schmitt
• 
  Midori Francis
  as Mika Yasuda
• 
  Kali Rocha
  as Sydney Heron
• 
  Debbie Allen
  as Catherine Fox
• 
  Dianne Doan
  as Molly Tran
• 
  Antonio Raul Garcia
  as Ian
• 
  Ashton Moio
  as Charlie Scott
• 
  Anne Ramsay
  as Wanda Gallagher
• 
  Brett Schaberg
  as Process Server
• 
  Laura Spencer
  as Lacey

Director:
Debbie Allen

Writer:
Meg Marinis