- Ellen Pompeo (Meredith Grey)
- Chandra Wilson (Miranda Bailey)
- James Pickens Jr. (Richard Webber)
- Caterina Scorsone (Amelia Shepherd)
- Camilla Luddington (Jo Wilson)
- Kevin McKidd (Owen Hunt)
- Kim Raver (Teddy Altman)
- Jason George (Ben Warren)
- Chris Carmack (Atticus Lincoln)
- Anthony Hill (Winston Ndugu)
- Adelaide Kane (Jules Millin)
- Alexis Floyd (Simone Griffith)
- Niko Terho (Lucas Adams)
- Harry Shum Jr. (Benson 'Blue' Kwan)
- Trevor Jackson (Wes Bryant)
Grey's Anatomy — S3E5
Episode: Oh, the Guilt
Air Date: 2006-10-19
Runtime: 43 min
Overview
Derek learns one of Addison's secrets. Bailey talks about motherhood and depression to a mother who is set to have cancer surgery and who seems to not care about any decisions concerning the future. A resident is fiercely questioned about the death of a male patient. An ex-couple meet before lunch and get stuck - Meredith and Addison work on their case. Things get awkward when the ex-couple's daughter, Michelle, arrives at the hospital.