- Seth MacFarlane (Peter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire (voice))
- Alex Borstein (Lois Griffin / Tricia Takanawa / Loretta Brown / Barbara Pewterschmidt (voice))
- Mila Kunis (Meg Griffin (voice))
- Seth Green (Chris Griffin (voice))
- Patrick Warburton (Joe Swanson (voice))
- Arif Zahir (Cleveland Brown (voice))
Family Guy — S6E4
Episode: Stewie Kills Lois (1)
Air Date: 2007-11-04
Runtime: 21 min
Overview
Lois and Peter sail off on a cruise. Jealous that he was left behind, Stewie's matricidal tendencies are rekindled. When Brian challenges him to actually do it, Stewie carries out his diabolical plan.