- Steven Weber (Dr. Dean Archer)
- Jessy Schram (Dr. Hannah Asher)
- Luke Mitchell (Dr. Mitchell 'Mitch' Ripley)
- Sarah Ramos (Dr. Caitlin Lenox)
- Darren Barnet (Dr. John Frost)
- S. Epatha Merkerson (Sharon Goodwin)
- Oliver Platt (Dr. Daniel Charles)
Episode: How Do You Begin to Count the Losses
Air Date: 2022-09-21
Runtime: 42 min
In the aftermath of Halstead's apartment fire, Marcel, Choi and Archer work together to try to save the survivors. Charles and Med's new fellow, Cuevas, help a paranoid patient.