- Steven Weber (Dr. Dean Archer)
- Jessy Schram (Dr. Hannah Asher)
- Luke Mitchell (Dr. Mitchell 'Mitch' Ripley)
- Sarah Ramos (Dr. Caitlin Lenox)
- Darren Barnet (Dr. John Frost)
- S. Epatha Merkerson (Sharon Goodwin)
- Oliver Platt (Dr. Daniel Charles)
Episode: It's All in the Family
Air Date: 2019-10-30
Runtime: 42 min
Dr. Manning's actions with a recent patient lead to serious repercussions. April and Noah disagree over a patient who is injured after a beating. Dr. Charles is visited by a childhood friend with a surprising revelation.